Provides fresh advances in prevention of nitrosamine formation in vitro and in vivo. Discusses mechanisms of N-nitroso compound formation and denitrosation. experiences the metabolism of nitrosamines and the amendment of DNA and proteins by way of the goods of metabolism. Examines the consequences of nutritional elements and different chemopreventive brokers on N-nitroso compound metabolism and carcinogenicity. Discusses using particular biomarkers of nitrosamine publicity in people and in animal versions and covers their position within the molecular epidemiology of tobacco-derived nitrosamines.
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