Even though there are lots of books on drug metabolism, Radiotracers in Drug Development is exclusive in explaining how radiotracers are used to explain a drug’s absorption, distribution, metabolism, and excretion (ADME). overlaying conventional and up to date applied sciences and functions, the publication takes a powerful commercial technique, discussing the fundamentals of scintillation counting and untangling a number of the information processing equipment usually particular to person brands.
The chapters comprise descriptions of the most recent micro-plate counters and the starting to be purposes of accelerator mass spectrometry, positron emission tomography, gamma-scintigraphy, and radioluminography. as well as describing how the analytical applied sciences paintings, the members clarify how the knowledge are interpreted and utilized in the drug registration approach.
A certain reference and coaching reduction crucial for each drug metabolism division or drug metabolism learn crew, the ebook presents perception into the use and perform of ADME in a fashion that's either instructive and functional. relocating simply around the limitations of biology, chemistry, and physics, this can be the one entire, interdisciplinary source overlaying the how-tos of utilising radiotracers in drug improvement. It offers specified info on how the technological know-how is proper to the registration process.
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